These differentiation defects are associated with a lack of proper cell cycle exit and Rb remaining hyper-phosphorylated (Favreau et al

These differentiation defects are associated with a lack of proper cell cycle exit and Rb remaining hyper-phosphorylated (Favreau et al., 2004), as well as a failure of Lamin A/C to relocate from the nucleoplasm to the nuclear lamina (Markiewicz et al., 2005). in K32del, R249W and L35P HIDEMs. (A) Distribution of Lamin B1 fluorescence intensity …
Continue reading These differentiation defects are associated with a lack of proper cell cycle exit and Rb remaining hyper-phosphorylated (Favreau et al