Tobias, Joshua Wang, Veronique Giroux, Kathryn E

Tobias, Joshua Wang, Veronique Giroux, Kathryn E. shown an explicit proliferation-differentiation gradient. Notch inhibition gathered undifferentiated basal keratinocytes with deregulated squamous cell differentiation in organoids. EoE patient-derived 3D organoids shown normal epithelial framework ex?in the lack of the EoE inflammatory milieu vivo. Arousal of esophageal 3D organoids with EoE-relevant cytokines led to a phenocopy of …
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4C)

4C). gammaherpesviruses and is positioned to stabilize a putative syntaxin-like package motif. To analyze the part of these DBs in membrane fusion, gH was mutated by amino acid substitution of the DB cysteines. Mutation of the EBV-specific DB resulted in diminished gH/gL cell surface manifestation that correlated with diminished B cell and epithelial cell fusion. …
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