Not unexpectedly, coordinated regulation of genes from major metabolic pathways (glycolysis, pentosesphosphate pathway, rate of metabolism of aminoacids and nucleotides), cell cycle control and MAP kinase pathway within samples but different for each tumor type became apparent (Number 2)

Not unexpectedly, coordinated regulation of genes from major metabolic pathways (glycolysis, pentosesphosphate pathway, rate of metabolism of aminoacids and nucleotides), cell cycle control and MAP kinase pathway within samples but different for each tumor type became apparent (Number 2). 3a: Genes down-regulated in zebrafish, 3b: Genes up-regulated in zebrafish.(TIF) pone.0037880.s003.tif (1.1M) GUID:?22C56A34-C2DD-422C-8F41-63DE0275CBB3 Figure S4: Affected …
Continue reading Not unexpectedly, coordinated regulation of genes from major metabolic pathways (glycolysis, pentosesphosphate pathway, rate of metabolism of aminoacids and nucleotides), cell cycle control and MAP kinase pathway within samples but different for each tumor type became apparent (Number 2)

Consistent with a role of PLK1?in targeting NUAK1 for degradation, we observed low levels of NUAK1 during the G2CM-phase (0C1?h time point), when PLK1 as well while cyclin A and B1 were elevated (Number 5A)

Consistent with a role of PLK1?in targeting NUAK1 for degradation, we observed low levels of NUAK1 during the G2CM-phase (0C1?h time point), when PLK1 as well while cyclin A and B1 were elevated (Number 5A). by reducing the population of cells in S-phase and mitosis, an effect that can be rescued by overexpression of a …
Continue reading Consistent with a role of PLK1?in targeting NUAK1 for degradation, we observed low levels of NUAK1 during the G2CM-phase (0C1?h time point), when PLK1 as well while cyclin A and B1 were elevated (Number 5A)