2012;366:1382C1392

2012;366:1382C1392. and were enriched in xenografts residual after platinum therapy. Low dose SGI-110 reduced the stem-like properties of ALDH+ cells, including their tumor initiating capacity, resensitized these OCSCs to platinum, and induced re-expression of differentiation-associated genes. Maintenance treatment with SGI-110 after carboplatin inhibited OCSC growth, causing global tumor hypomethylation and decreased tumor progression. Our work …
Continue reading 2012;366:1382C1392

Supplementary MaterialsSupplementary Statistics

Supplementary MaterialsSupplementary Statistics. mechanisms in charge of tumor recurrence and poor prognosis in a number of cancer tumor types.1, 2, 3 Paclitaxel (PTX) is a tubulin-disrupting medication in the administration of an array of tumors.4, 5, 6 Although research have got uncovered the systems of PTX level of resistance in a number of malignancies, many …
Continue reading Supplementary MaterialsSupplementary Statistics